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Listing 6.06

Nephrotic syndrome

This listing covers nephrotic syndrome, a kidney problem where large amounts of protein leak into the urine, causing low blood protein and severe body-wide swelling (anasarca).

Read the full plain-language explanation

You must meet BOTH part A (lab tests showing heavy protein loss, documented twice at least 90 days apart within 12 months) AND part B (massive swelling lasting at least 90 days despite treatment).

Read Listing 6.06 on ssa.gov

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What Listing 6.06 asks for

What SSA looks for — see the 2 items

We will check your records against each of these. Every item comes straight from SSA's own listing.

    • Lab tests must show heavy protein loss in ONE of two ways:
    • 10 grams or more of protein in your urine per 24 hours
    • Serum albumin of 3.0 g/dL or less PLUS either 3.5 grams or more of protein per 24 hours or a urine protein-to-creatinine ratio of 3.5 or more.
    • The findings must be documented at least twice, at least 90 days apart, within one 12-month period.
    • Only one of the two lab paths is needed, but Part A AND Part B are both required.
    Read the original wording

    Lab tests must show heavy protein loss in ONE of two ways: (1) 10 grams or more of protein in your urine per 24 hours; or (2) serum albumin of 3.0 g/dL or less PLUS either 3.5 grams or more of protein per 24 hours or a urine protein-to-creatinine ratio of 3.5 or more. The findings must be documented at least twice, at least 90 days apart, within one 12-month period. Only one of the two lab paths is needed, but Part A AND Part B are both required.

    (Listing 6.06, criterion A)

    • You must also have anasarca — massive swelling over much of your body — that has lasted at least 90 days even though you are following prescribed treatment.
    • Doctors' notes should describe where the swelling is (such as in front of the shins, around the eyes, or over the lower back) and any fluid around the lungs, belly, or heart.
    Read the original wording

    You must also have anasarca — massive swelling over much of your body — that has lasted at least 90 days even though you are following prescribed treatment. Doctors' notes should describe where the swelling is (such as in front of the shins, around the eyes, or over the lower back) and any fluid around the lungs, belly, or heart.

    (Listing 6.06, criterion B)

How long it must last:

Laboratory findings must be documented on at least two occasions at least 90 days apart during a consecutive 12-month period, and anasarca must persist at least 90 days despite prescribed treatment; the general 12-month disability duration expectation also applies.