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Listing 14.06

Undifferentiated and mixed connective tissue disease

This listing covers autoimmune conditions that mix features of several diseases (like lupus, vasculitis, and rheumatoid arthritis) without fully matching any one of them.

Read the full plain-language explanation

Diagnosis is based on clinical features plus blood tests such as rheumatoid factor or antinuclear antibody. SSA looks for involvement of two or more organs or body systems with constant symptoms, or repeated flare-ups that seriously limit functioning. Only one path (A or B) needs to be met.

Read Listing 14.06 on ssa.gov

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What Listing 14.06 asks for

What SSA looks for — see the 2 items

We will check your records against each of these. Every item comes straight from SSA's own listing.

    • Your connective tissue disease affects at least two organs or body systems, one at least moderately, and you have at least two constant symptoms: severe tiredness, fever, feeling ill, or unintentional weight loss.
    • Only one of paths A or B is needed.
    Read the original wording

    Your connective tissue disease affects at least two organs or body systems, one at least moderately, and you have at least two constant symptoms: severe tiredness, fever, feeling ill, or unintentional weight loss. Only one of paths A or B is needed.

    (Listing 14.06, criterion A)

    • Your disease flares up repeatedly, you have at least two constant symptoms (severe tiredness, fever, feeling ill, or unintentional weight loss), and it seriously limits your daily activities, social functioning, or ability to finish tasks on time.
    • Only one of paths A or B is needed.
    Read the original wording

    Your disease flares up repeatedly, you have at least two constant symptoms (severe tiredness, fever, feeling ill, or unintentional weight loss), and it seriously limits your daily activities, social functioning, or ability to finish tasks on time. Only one of paths A or B is needed.

    (Listing 14.06, criterion B)

How long it must last:

No listing-specific duration is stated; the impairment must have lasted or be expected to last at least 12 months (the general SSA duration requirement).